This blog posts new scientific literature and our articles, starting in 2010. See also the overview of histamine intolerance literature (pdf file).

Histamine intolerance: a metabolic disease?

May 4, 2010

OBJECTIVE: To evaluate the evidence regarding the disease concept of histamine intolerance as a state of inadequate histamine inactivation.
METHODS: Keyword-based systematic screening of the scientific literature and of public websites focusing on diagnostic and therapeutic procedures.
RESULTS: Histamine intolerance is commonly diagnosed based solely on subjective reporting of symptoms instead of following systematic diagnostic procedures based on objective laboratory and physical parameters. The only effective long-term therapy is avoidance of histamine-containing food.
CONCLUSIONS: The concept of histamine intolerance as a metabolic disease is in need of more experimental and clinical evidence and affected patients will benefit from a clear, evidence-based diagnostic and therapeutic regime.

[Schwelberger H.G., Inflamm Res. 2010 Mar;59 Suppl 2:S219-21]

 

Amines

April 28, 2010

This book chapter gives an overview of the chemical analysis of biogenic amines and polyamines in dairy food. It includes a table with contents of amines in different types of cheese.

Tomรกลก Komprda and Vlastimil Dohnal, Chapter 41 in: L.M. Nollet, F. Toldra (editors), Handbook of Dairy Food Analysis, CRC Press, Taylor and Francis, ISBN: 9781420046311 (in press, 2010)


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Effects of a pseudoallergen-free diet on chronic spontaneous urticaria: a prospective trial

March 30, 2010

BACKGROUND: Chronic spontaneous urticaria is a skin disorder that is difficult to manage and can last for years. 'Pseudoallergens' are substances that induce hypersensitive/intolerance reactions that are similar to true allergic reactions. They include food additives, vasoactive substances such as histamine, and some natural substances in fruits, vegetables and spices. Eliminating pseudoallergens from the diet can reduce symptom severity and improve patient quality of life. AIM: To assess the...


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